Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone

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Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone

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Title: Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone
Author: Fischer, David
Advisor: Sternberg, Wendy
Department: Haverford College. Dept. of Psychology
Type: Thesis (B.A.)
Issue Date: 2010
Abstract: Dominant male rodents exhibit higher neurogenesis rates than subordinate rodents. Elevated testosterone levels lead to similar increases in neurogenesis. The current study investigated the relative contribution of testosterone versus social factors to dominance-related neurogenesis. Castrated mice were administered a high dose of testosterone (HT), a low dose (LT), or an oil vehicle (OIL). Mice were then housed individually or in groups to establish dominance hierarchies. Levels of aggression, testosterone, corticosterone and neurogenesis were assessed. While HT mice exhibited the highest testosterone levels, LT mice the most aggression, and OIL mice the most corticosterone, no neurogenesis differences were found.
Subject: Developmental neurobiology
Subject: Social hierarchy in animals
Subject: Dominance (Psychology)
Subject: Testosterone -- Physiological effect
Terms of Use: http://creativecommons.org/licenses/by-nc/3.0/us/
Permanent URL: http://hdl.handle.net/10066/4943

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Fischer, David. "Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone". 2010. Available electronically from http://hdl.handle.net/10066/4943.

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